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A difficult case |
Consultant Neurologist, The Royal London Hospital, Whitechapel, London E1 1BB, UK; Jeffrey.Gawler@bartsandthelondon.nhs.uk
| The first 150 words of the full text of this article appear below. |
I saw Tony first in the autumn of 1994, when he was 30 years of age. In June 1994, two major seizures, which were preceded by right facial twitching, had led to admission elsewhere; an MR scan of his brain (unenhanced) and spinal fluid analysis were normal, but an electroencephalogram (EEG) showed a left temporal slow wave focus. He had been treated with carbamazepine but ongoing focal seizures, which involved jerking of the right face, neck, and shoulder, had led to the addition of phenytoin, gabapentin, and clonazepam (none of which appeared to influence the frequency of his attacks).
During the consultation there were repeated episodes of right perioral twitching, without change of awareness or his speech. Examination revealed minor uncoordination of his right hand but no other abnormal neurological signs. Systemic examination was normal. His blood count and biochemical profile were normal; he was immunocompetent. His EEG showed continuous
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