Practical Neurology

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Practical Neurology 2007;7:306-314; doi:10.1136/jnnp.2007.129080
Copyright © 2007 by the BMJ Publishing Group Ltd.
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Clinicopathological conference

Clear cell carcinoma of the kidney in a young man with neurological complications

C L Hirst, Specialist Registrar in Neurology1, G N Fuller, Consultant Neurologist2, G A Lammie, Consultant Pathologist3, T A T Hughes, Consultant Neurologist1

1 Department of Neurology, University Hospital of Wales, Cardiff, UK
2 Department of Neurology, Gloucester Royal Hospital, Gloucester, Gloucestershire, UK
3 Department of Pathology, University Hospital of Wales, Cardiff, UK

Correspondence to:
Correspondence to:
Dr T Hughes
Consultant Neurologist, Department of Neurology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN, UK; Tom.hughes@cardiffandvale.wales.nhs.uk

The first 150 words of the full text of this article appear below.

A 43-year-old man presented in April 2004 with a six-week history of a runny nose and a "cold", and for three weeks he had also been feeling generally unwell with mild vertigo, tinnitus and unsteadiness; the latter symptoms had worsened over a week but had not progressed for two weeks. On examination his blood pressure was 120/70, he was afebrile, and there was no meningism. He was orientated, and told his own story. Fundoscopy was normal. There was fine gaze-evoked bilateral horizontal nystagmus and obvious ataxia of his upper and lower limbs and gait. General medical examination, including the testicles and skin, was normal.

THE FIRST TESTS

He was extensively investigated and the following tests were normal or negative: full blood count, urea and electrolytes, liver function (alkaline phosphatase 52 IU/l (30–115), aspartate transaminase 31 IU/l (5–45)), thyroid function, ANCA, anti-dsDNA antibodies, C-reactive protein, vitamin B12 and folate, calcium, chest x ray, 12-lead . . . [Full text of this article]


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EDITOR’S CHOICE
Charles Warlow
Practical Neurology 2007 7: 279. [Extract] [Full Text] [PDF]





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Copyright © 2007 by the BMJ Publishing Group Ltd.